| Gastric parietal cell antibodies | |||||
| Registration Code | TAA | ||||
| Method | Indirect immunofluorescence | ||||
| Synonyms | GPC antibodies |
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| Constituent Tests | |||||
| Refer to Group` | $Tissue autoantibody screen | ||||
| Price | Refer to Group | ||||
| Specimen collection | |||||
| Advanced Notice | No | ||||
| Patient Preparation | No | ||||
| Patient Sample | 5 mL clotted blood (EDTA, Citrate and Heparin may be used) | ||||
| Paediatric Sample | 0.5 mL clotted blood | ||||
| Unacceptable Samples | |||||
| Sample Delivery to Lab | Room temperature | ||||
| In the Laboratory | |||||
| Preferred Aliquot | 1 mL serum | ||||
| Minimum Aliquot | 100 uL serum | ||||
| Aliquot Storage | Fridge | ||||
| Aliquot Transport to CHL | Room temperature | ||||
| When Analysed | Mon - Fri, business hours only | ||||
| Turnaround Time | 2 - 3 days | ||||
| Contact Details | Biochemistry-Immunology
| Interpretation
| Reference range: Not detected
| See Comments. Comments
| Positive in 90% of patients with pernicious anaemia. Other disorders that may be associated with GPC antibodies are atrophic gastritis (up to 60%), autoimmune thyroid diseases (33%), diabetes mellitus (12%), and rarely iron deficiency anaemia. Although detected in less than 2% of the normal population under 20, the incidence of GPC antibodies increases in women over the age of 40 and may be present in up to 16% of the normal population over 60 years of age.
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