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Agitation
- Attempt to identify and reverse causes.
- Exclude acute delirium and treat if required as per Delirium Section.
- Manage any symptoms of acute anxiety.
- Spiritual, social and religious issues require a multi-disciplinary approach.
- Precipitants such as fear (requiring explanation and reassurance or the presence of a relative) or unrelieved physical symptoms must be addressed, e.g. constipation, urinary retention, and alcohol or nicotine withdrawal.
- An antidepressant may need to be considered.
Treatment with benzodiazepines may be necessary:
- Clonazepam 0.25 – 1 mg nocte – tabs or oral drops 0.1 mg/drop (1-5 drops q6h prn).
- Lorazepam 0.5 - 2 mg PO/SL, 4 - 6 hourly.
- Diazepam 2 - 10 mg PO or PR, 8 - 12 hourly.
Note: Sedation may occasionally be indicated in the terminally ill when agitation or extreme fear is unrelieved – a referral to the Palliative Care Service is strongly recommended. See Terminal Agitation Section.
Caution: Clonazepam has a long half-life and can accumulate in repeated dosing.
Topic Code: 4139